Look at enough supplement labels and you'll eventually see a line like "Focus Blend: 800mg" followed by a list of five or six ingredient names, with no individual amounts given. That's a proprietary blend, and it's one of the most common ways a supplement label can be technically legal while still leaving you unable to evaluate what you're actually taking.
A proprietary blend is a mix of two or more ingredients grouped under one name with a single combined weight disclosed, instead of listing the amount of each ingredient separately. FDA labeling rules require dietary supplement ingredients to be listed in descending order of predominance by weight (FDA Dietary Supplement Labeling Guide), and blends technically comply with this because the ingredients are still named in that descending order. What's missing is the individual dose for each one.
That gap is the entire problem. A blend might list five plants under one combined weight, and there is no way to know from the label whether one plant makes up 450mg of the real active ingredient while the rest are filler amounts of 10mg each. The FDA's own labeling guidance confirms that combined blend weight, not individual amounts, is all that's legally required for proprietary blends (FDA Dietary Supplement Labeling Guide).
There are a few recurring reasons a brand chooses a blend over full disclosure.
Some brands argue a blend protects a unique combination ratio from being copied. This is a legitimate business reason, but it comes at the direct cost of consumer transparency, and the two interests are in tension.
This is the more concerning reason. If five ingredients are combined under one large-sounding total weight, the product can appear more potent than it is. A consumer sees "1,200mg proprietary energy blend" and assumes every ingredient inside is present at a meaningful dose. Often, one or two ingredients dominate the weight while others are included at token amounts, sometimes called "fairy dusting," just enough to legally list the ingredient on the label without it doing much of anything.
Many active ingredients have a minimum dose used in clinical research to produce an effect. If a brand can't afford, or doesn't want, to include an ingredient at that clinically relevant amount, hiding it inside a blend avoids the obvious comparison between the label and the research.
You cannot evaluate what you're taking if you don't know how much of it you're taking. This isn't a minor inconvenience, it undermines the entire purpose of reading a label in the first place.
It also makes stacking supplements riskier. If you're combining multiple products and don't know the actual dose of a shared or overlapping ingredient, like caffeine, a stimulant blend, or an herbal extract, you have no reliable way to estimate your total daily intake or check for interactions.
Consumer advocates and researchers who study supplement labeling consistently flag proprietary blends as a red flag: when a company hides individual doses behind a blend, there's no way for an outside party, or the buyer, to confirm the formula is dosed at a meaningful, research-backed level.
The alternative to a proprietary blend isn't complicated, it's just full disclosure of every ingredient's exact amount. Several brands have built their entire reputation around this.
Legion Athletics discloses every ingredient at a clinically dosed amount, with every batch tested for purity through Labdoor certification. Transparent Labs publishes third-party test results and avoids proprietary blends entirely across its sports supplement line. Kaged is fully transparent and clinically dosed, with no proprietary blends and Informed Sport certification on every batch.
Compare that to AG1/Athletic Greens, which is NSF Certified for Sport and batch-tested for contaminants, a real positive, but still keeps most of its ingredient doses hidden inside proprietary blends. Certification and full dose transparency are two different things, and a brand can have one without the other.
Look at the Supplement Facts panel. If you see a bolded or named group (like "Complex," "Blend," or "Matrix") followed by a single total weight and then several ingredient names listed underneath without their own numbers, that's a proprietary blend. If every ingredient instead has its own milligram or gram amount listed individually, the label is fully disclosed.
Are proprietary blends illegal? No. They comply with FDA labeling rules as long as ingredients within the blend are listed by name in descending order, even without individual amounts disclosed (FDA).
Does a proprietary blend mean the product doesn't work? Not necessarily, but it means you can't verify whether it works based on the label alone. Some blends do contain meaningful doses of every ingredient; you simply have no way to confirm that from the packaging.
Can I ask a company for the individual doses in their blend? You can ask, but companies aren't required to disclose it, and many won't, since protecting the exact ratio is often the whole point of using a blend.
Is there ever a good reason to use a proprietary blend? Some brands argue it protects intellectual property in a competitive formulation. That may be true, but it still shifts risk onto the consumer, who loses the ability to verify dosing.
How common are proprietary blends in supplements? They're especially common in pre-workout formulas, "energy" and "focus" blends, and some greens powders and weight-management products, categories where marketing a large-sounding total weight is a common sales tactic.
Once you know how to spot a proprietary blend, the next step is tracking what you're actually taking across every product in your routine. The Cade app lets you log your supplements and peptides and check for potential interactions in one place.