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Visbiome

76/100

A medical-food probiotic with 100+ trials behind its formulation, sold as a cold-chain product

Visbiome isn't a wellness-aisle probiotic — it's the De Simone Formulation, an 8-strain blend the company describes as the most studied multi-strain probiotic available, positioned for conditions like IBS, IBD, and pouchitis under physician guidance (Visbiome).

Total potency is disclosed per SKU: GI Care capsules at 112.5 billion CFU, Advanced GI Care powder at 450 billion CFU, Extra Strength at 900 billion CFU, and GI Care Kids at 225 billion CFU — though the 8 strains are presented as a blend without a per-strain CFU breakdown (Visbiome).

The core quality-control story is cold-chain integrity: product ships and stores under refrigeration with a temperature-monitoring sensor to protect potency (Visbiome). No NSF/USP certification or published batch COAs were found, though ConsumerLab covers it as a reviewed brand (ConsumerLab).

No recalls or enforcement actions on record. The real nuance is that Visbiome is a medical food meant for use under doctor supervision, and it carries the well-documented lineage dispute with VSL#3 that ConsumerLab addresses directly (ConsumerLab). If you want a general daily probiotic rather than a clinician-directed one, BioGaia or Pendulum fit that use case better.

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